Nykko Sorry for the late response, PoE has had my attention since the league started. Make sure your all of your resistances are capped (you take extra damage if you are lower than 75% on area level 100) and up your endurance % and threshold. The threshold is how much life it will cover so in your case 246 (you need 411 because you have 1246hp) and endurance % is the damage reduction received on damage taken when life is lower than your threshold.
Also look to keep Reaper and the Bone Armor from Transplant up as much as possible.
Edit: you can also invest into a shield for block