Levelling
Like usual, early game you want to be prioritizing Resistances > Health > Move Speed, upgrading to higher armor bases as you progress.
Added SuffixHealth and Increased SuffixHealth affixes are top priority for Helm, Body, and Belt. While resists can be solved with affixes applied via forge to any other piece of gear.
Since you'll be using Hammer Throw to level through the campaign, I recommend two Silver Rings or Gold Rings with PrefixThrowing Damage and Reduced Mana Cost. Once you can get both with that affix at T5 plus any resists you can afford to add, these rings should last you all the way to transitioning to Warpath.
SuffixAll Resistances While Channelling, SuffixAll Resistances, and SuffixElemental Resistance are also good stopgaps while levelling for obvious reasons.
Monoliths
Block
Once you transition to Warpath, the real game begins. The first thing you want to do is reach 100% block chance. You achieve this by using a high block chance shield such as Ironglass Shield, with T5+ PrefixBlock Chance, and getting T5 SuffixBlock Chance and Effectiveness on both Rings and Gloves. PrefixHealth Gained on Block is also a requirement on your shield since it's the only piece of gear that can get it, so make sure that's in your loot filter. Another bump to block chance and health on block can be Solarum Banner, but only as a stopgap before transitioning to Solar Commandment. You also want a SuffixDamage Taken on Block on your shield for high-end content.
Damage
Scaling damage is pretty straightforward. PrefixFire Damage + PrefixSpell Damage or PrefixElemental Damage on a Crystal Wand will be your main source of scaling, and the wand itself will reduce Smite's cost to 0, allowing for infinite Warpath channeling. A good PrefixFire Penetration amulet will really help boost up the damage, and can remain even if you want to transition do a DoT variant of the build. PrefixFire Damage should be prioritized on all accessories. Two Ruby Rings are recommended.
Crit Avoidance
Getting SuffixChance to Blind on Hit on your Wand will keep you safe until you can cap out your crit avoidance.
Speaking of which, after you cap resists, work towards adding SuffixCritical Strike Avoidance (at least 30% total) on at least one piece of gear - most likely Boots. the rest should be covered by a high-rolled Grand Survival of Might from empowered Reign of Dragons.
Health
Get Health on all gear that you can afford to without compromising resists. If possible, your Body, Helm, and Belt should have both Added SuffixHealth and Increased SuffixHealth suffixes. You want around
Resists
Resists are straightforward; get to at least 100% on all resists. The SuffixAll Resistances shield suffix will assist with this until you can cover everything with other gear since the suffixes you really want are SuffixDamage Taken on Block and SuffixHealth.
There are also some of double-resist implicit pieces such as Bone Amulet that are great choices.
Poison resist is one of the toughest things to solve for on any Sentinel, however the Carapace Shield can help you cheat it up to the cap of 75%, and is also a fairly high block-chance base.